Determination of active components from selected plants used in traditional medicine in Nigeria by GC-MS screening

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Vol. 7 No. 1 (2023)
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Articles

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MICHAEL SUNDAY ABU ♥
Department of Biochemistry, Faculty of Pure and Applied Sciences, P.M.B 1020, Wukari, Federal University Wukari. Taraba State, Nigeria
RUKAIYAT LAWAL MASHI
Department of Biological Science, Federal College of Education. Dutsin-ma Road, Katsina Kastina-Nigeria
JAMILA YAHAYA LAWAL
Department of Biological Science, Federal College of Education. Dutsin-ma Road, Katsina Kastina-Nigeria
ELIZABETH HABU EZEKIEL
Department of Biochemistry, Faculty of Pure and Applied Sciences, P.M.B 1020, Wukari, Federal University Wukari. Taraba State, Nigeria

Abstract

Abstract. Abu MS, Mashi RL, Lawal JY, Ezekiel EH. 2023. Determination of active components from selected plants used in traditional medicine in Nigeria by GC-MS screening. Cell Biol Dev 7: 9-19. Herbal products have been utilized extensively in treating various ailments for centuries. Because of the enormous range of functionally relevant secondary metabolites of microbial and plant species, natural products and related structures are critical sources for discovering novel medications. The study investigated the phytoconstituents of extract of selected plants commonly used in traditional medicine in Nigeria, which include: bitter leaf (Vernonia amygdalina Delile), ginger (Zingiber officinale Roscoe), turmeric (Curcuma longa L.), bitter kola (Garcinia kola Heckel), Garlic (Allium sativum L.) and a mixture of all (turmeric, garlic, ginger, bitter leaf and bitter kola) using GC-MS (gas chromatography-mass spectrometry). GC-MS analysis was performed using Agilent 6890 GC with 59739N MSD and GC-MS equipped with Elite-I fused with silica capillary column (Cpsil 8cb: 30 mm x 25 mm x 0.25 mm). The carrier gas was Helium at a 1.5 mL/min flow rate. The sample was injected at a volume of 1 ?L. The results of the analysis confirmed the presence of several compounds. The most prevailing compounds of medicinal value are Hexadecanoic acid, Cis-9,cis-12-Octadecadienoic acid, Squalene, Octanoic acid, Benzene, Pentanoic acid, beta.-Bisabolene, Nonanoic acid, aR-Turmerone, (3R,3aR,7R,8aS)-3,8,8-Trimethyl-6- methyleneoctahydro-1H-3a, Undecanoic acid, 2-Pentadecanone, Benzenedicarboxylic acid, Phytol, Linoleic acid, Dotriacontane, 1,3-Cyclohexadiene, 1,3-Cyclohexadiene, 2,6-Octadienal, 7-Propylidene-bicyclo4.1.0, Butan-2-one, 3-Cyclohexen-1-carboxaldehyde, (E)-1-(6,10-Dimethylundec-5-en-2-yl)-4-methylbenzene, 1-Decanol, Tetratetracontane, Caparratriene, Squalene, 9,19-Cyclolanost-24-en-3-ol. The evaluated plants showed the presence of various biologically active compounds as the scientific background of their use in traditional medicine.

2017-01-01

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