Effect of palm sap (Arenga pinnata) on blood glucose levels of mice (Mus musculus) alloxan-induced diabetic
##plugins.themes.bootstrap3.article.sidebar##
Issue
Section
Articles
##plugins.themes.bootstrap3.article.main##
Abstract
Abstract. Liputo SM, Lamondo D, Solang M. 2021. Effect of palm sap (Arenga pinnata) on blood glucose levels of mice (Mus musculus) alloxan-induced diabetic. Asian J Nat Prod Biochem 20: 11-15. This study aims to determine the effect of palm sap (Arenga pinnata (Wurmb) Merr.) in reducing blood glucose levels in alloxan-induced diabetic mice (Mus musculus Linnaeus, 1758). Twenty-five mice aged 2-3 months were grouped into a negative control group, a positive control group, and a palm sap group (0.2 mL, 0.4 mL, and 0.6 mL). The result showed that the palm sap with a dose of 0.4 mL was the most significant in reducing blood glucose levels. This study concluded that the administration of palm sap affected decreasing blood glucose levels (p <0.05).
##plugins.themes.bootstrap3.article.details##
References
Ajebli M, Khan H, Eddouks M. 2021. Natural alkoloids and diabetes mellitus: A review. Endocr Metab Immun Disord Drug Targets 21 (1): 111-130. DOI: 10.2174/1871530320666200821124817.
Aprila IF, Salim MN, Daud R, Armansyah T, Asmilia N, Jamin F. 2015. Pengaruh pemberian kacang panjang (Vigna unguiculata) terhadap kadar glukosa darah mencit (Mus musculus) yang diinduksi aloksan. J Medika Veterenia 9(2): 97-99. DOI: 10.21157/j.med.vet.v9i2.3983. [Indonesian]
Bahman DS, Yuliet, Ihwan. 2019. Efek akar Garcinia rostrata Hassk.ex Hook.f terhadap penurunan kadar glukosa darah puasa mencit jantan (Mus musculus) yang diinduksi aloksan. Biocelebes 13 (1): 21-29. [Indonesian]
Choong CC, Anzian A, Sapawi CW, Hussin M. 2016. Characterization of Sugar from Arenga pinnata and Saccharum officinarum Sugars. Intl Food Res J 23 (4): 1642-1652.
Fitriani LI, Murbawani E, Nissa C. 2018. Hubungan asupan vitamin C, vitamin E dan B-karotendengan kadar gula darah puasa pada wanita usia 35-50 tahun. J Nutr Collage 7 (2): 84-91. DOI: 10.14710/jnc.v7i2.20827. [Indonesian]
Gannon MC, Nuttal FQ, Saeed S, Jordan K, Hoover H. 2003. An increase in dietary portein improves the blood glucose response in persons with type 2 diabetes. Am J Clin Nutr 78: 734-741. DOI: 10.1093/ajcn/78.4.734.
Gunawan R, Ramadhan UG, Iskandar J, Partasasmita R. 2017. Local knowledge of utilization and management of sugar palm (Arenga pinnata) among Cipanggulaan People of Karyamukti, Cianjur (West Java, Indonesia). Biodiversitas 19: 93-105. DOI: 10.13057/biodiv/d190115.
Hikmah N, Yuliet, Khaerati K. 2016. Pengaruh pemberian ekstrak daun salam (Syzygium polyanthum Wight.) terhadap glibenklamid dalam menurunkan kadar glukosa darah mencit (Mus musculus) yang diinduksi aloksan. Galenika J Pharm 2 (1): 24-30. DOI: 10.22487/j24428744.2016.v2.i1.5300. [Indonesian]
Hu X, Wang S, Xu J, Wang D-B, Chen Y, Yang G-Z. 2014. Triterpenoid saponins from Stauntonia chinensis Ameliorate insulin resistance via the AMP-Activated Protein Kinase and IR/IRS-1/PI3K/Akt pathways in insulin-resistant HepG2 cells. Intl J Mol Sci 15: 10446-10458. DOI: 10.3390/ijms150610446.
International Diabetes Federation (IDF). 2019. IDF Diabetes Atlas. Diakses 18 januari 2020 www.diabetesatlas.org [Indonesian]
Ismail, Yurnia NN, Solang M, Uno WD. 2020. Komposisi proksimat dan indeks glikemik nira aren. Biospecies 13 (2): 1-9. DOI: 10.22437/biospecies.v13i2.8761. [Indonesian]
Kandowangko, Novri Y, Solang M, Ahmad J. 2011. Kajian Etnobotani Tanaman Obat oleh Masyarakat Kabupaten Bonebolango Provinsi Gorontalo. Laporan Penelitian Etnobotani Tanaman Obat Jurusan Biologi Universitas Negeri Gorontalo, Gorontalo. [Indonesian]
Kurniawan T, Jayanudin, Kustiningsih I, Firdaus MA. 2018. Palm sap sources, characteristic, and utilization in Indonesia. J Food Nutr Res 6 (9): 590-596. DOI: 10.12691/jfnr-6-9-8.
Larsson SC, Wolk A. 2007. Magnesium intake and risk of type 2 diabetes: A meta-analysis. J Intern Med 262: 208-214 DOI: 10.1111/j.1365-2796.2007.01840.x.
Lempang M, Mangopang AD. 2012. Efektivitas nira aren sebagai bahan pengembang adonan roti. J Penelitian Kehutanan Wallacea 1 (1): 26-35. DOI: 10.18330/jwallacea.2012.vol1iss1pp26-35. [Indonesian]
Lempang M. 2012. Pohon aren dan manfaat produksinya. Info Teknis Eboni 9 (1): 37-54. [Indonesian]
Maha MH. 2013. Potentialty of vitamin C and/or lupinus termis to modulate blood glucose level and oxidative stress status of alloxan-induced diabetic rats. Sci J Biol Sci 2 (11): 41-46
Mulatsih ES. 2020. Hubungan Asupan Magnesium dengan Kadar Glukosa Darah pada Penderita Diabetes Mellitus Tipe II Di Puskesmas Tawangsari Sukoharjo. [Skripsi]. Fakultas Ilmu Kesehatan, Univeritas Muhammadiyah Surakarta. [Indonesian]
Oboh G, Ademosun AO. 2011. Shaddock peels (Citrus maxima) phenolic extracts inhibit ?-amylase, ?-glucosidase and angiotensin I-converting Enzym Activities: Anutraceutical approach to diabetes management. Diabetes Metab Syndr 5: 148-152. DOI: 10.1016/j.dsx.2012.02.008.
Parwata A, Laksmiwati, Dina MN, Yasa S. 2018. The contens of phenol and flavonoid compounds in water extract of Gyrinops versteegii leaves have potentially as natural antioxidants and hypoglicemic in hyperglycemic wistar rats. Biochem Pharmacol 11 (3): 1543-1552. DOI: 10.13005/bpj/1521.
Prastari C,Yasni S, Nurilmala M. 2017. Karakteristik protein ikan gabus yang berpotensi sebagai antihiperglikemik. JPHPI 20 (2): 413-423. DOI: 10.17844/jphpi.v20i2.18109. [Indonesian]
Pratama NA, Busman H. 2020. Potensi antioksidan kedelai (Glycine Max L) terhadap penangkapan radikal bebas. J Ilmiah Kesehatan Sandi Husada 11 (1): 497-504. DOI: 10.35816/jiskh.v11i1.333. [Indonesian]
Putra AP. 2013. Pengaruh Pemberian Ekstra Etanol Buncis (Phaseolus vulgaris L.) terhadap Penurunan Kadar Glukosa Darah Menict yang Diinduksi Aloksan. [Skripsi]. Fakultas Kedokteran, Universitas Jember, Jember. [Indonesian]
Putra, Achmad A, Rachma H. 2017. Kejadian efek samping potensial terapi obat anti diabetes pasien diabetes melitus berdasarkan Algoritma Naranjo. Pharm J Indonesi 2 (2): 45-50. DOI: 10.21776/ub.pji.2017.002.02.3. [Indonesian]
Putri IDAEW, Ratnayanti IGAD, Sugiritma IW, Arijana IGKN. 2020. Analisis fitokimia nira aren dan tuak aren (Arenga pinnata (Wurmb) Merr.). J Medika Udayana 10 (6): 18-22. [Indonesian]
Rasouli H, Yarani R, Paciot F, Popovic-Djordjevic J. 2020. Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perpectives. Pharmacol Res 155: 104723. DOI: 10.1016/j.phrs.2020.104723.
Riskesdas. 2018. Laporan Nasional Riskesdas 2018. Balitbangkes. Accessed January 18, 2020 www.labdata.litbang.kemkes.go.id
Rudiawan A. 2016. Pengaruh Aktivitas Fisik Maksimal terhadap Peningkatan Jumlah Leukosit Pada Tikus Putih (Rattus Norvegius Wistar). [Diploma Thesis]. Universitas Negeri Malang, Malang. [Indonesian]
Sari ADP, Kusuma H, Ratri DMN, Wibisono C, Suprapti B. 2020. The effect of premixed insulin to blood glucose concentration in patients with type 2 diabetes mellitus. J Basic Clin Physiol Pharmacol 2020: 20190342. DOI: 10.1515/jbcpp-2019-0342.
Wisudanti DD. 2016. Aplikasi terapeutik geraniin dari ekstrak kulit rambutan (Nephelium lappaceum) sebagai anthiperglikemik melalui aktivitasnya sebagai antioksidan pada diabetes melitus tipe 2. Nurseline J 1 (1): 120-138. [Indonesian]
World Health Organization (WHO). 2004. Guidelines For The Regulation Of Herbal Medicines In The South-East Asia Region. accessed on 17 November 2020 https://apps.who.int/iris/handle/10665/205175
Yuslianti ER. 2017. Pengantar Radikal Bebas dan Antioksidan. Deepublish, Yogyakarta. [Indonesian]
Yusni, Akbar IB, Rezania, Fahlevi R. 2017. Penurunan kadar gula darag akibat pemberian ektrak manggis (Gracinia mangostana) dan tomat (Lycopersicum esculentum Mill) pada tikus diabetes. Glob Med Health Commun 5 (1): 57-63. DOI: /10.29313/gmhc.v5i1.2097.