Ethnomedicine, improved traditional medicine from Cocos nucifera water and evaluation of antibacterial activity on four bacterial strains in Center, Cameroon

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DOI https://doi.org/10.13057/biofar/f220104
Issue
Vol. 22 No. 1 (2024)
Section
Articles

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GEORGES MAXIME LAMY LAMY ♥
Institute of Medical Research and Medicinal Plants Studies (IMPM). PO Box 13033 Yaoundé, Cameroon
JULIENNE LOUISE NGO LIKENG
High Institute of Sciences and Techniques Applied to Health (ISSTAS). PO Box 33422 Yaoundé, Cameroon
ROSETTE CHRISTELLE NDJIB
Institute of Medical Research and Medicinal Plants Studies (IMPM). PO Box 13033 Yaoundé, Cameroon
SANDRINE EMILIE NGO NDOUNGA
High Institute of Sciences and Techniques Applied to Health (ISSTAS). PO Box 33422 Yaoundé, Cameroon
L’AFRICAINE BLANCHE ELOMO
Paramedical Training Center. PO Box 25602 Yaoundé, Cameroon
SALIOH M. MBUH
Institute of Medical Research and Medicinal Plants Studies (IMPM). PO Box 13033 Yaoundé, Cameroon
LEILA SANDRA NNANGA
Institute of Medical Research and Medicinal Plants Studies (IMPM). PO Box 13033 Yaoundé, Cameroon
MAHAMA
Local Co-Author, Local Counterpart for Informants who Participated by Name
JACQUES BRUNO NGOTTA BIYON
Departement of Plant Biology, Faculty of Sciences, University of Douala. PO Box 24157, Douala, Cameroon
KARL HARMSEN
Marderhoek 41, NL-8223 XC Lelystad, Netherlands
EMMANUEL NNANGA NGA
Department of Galenic Pharmacy and Pharmaceutical Legislation, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I. PO Box 812 Yaoundé, Cameroon
ALEMBERT TIABOU TCHINDA
Institute of Medical Research and Medicinal Plants Studies (IMPM). PO Box 13033 Yaoundé, Cameroon

Abstract

Abstract. Lamy GML, Likeng JLN, Ndjib RC, Ndounga SEN, Elomo LB, Mbuh SM, Nnanga LS, Mahama, Biyon JBN, Harmsen K, Nga EN, Tchinda AT. 2024. Ethnomedicine, improved traditional medicine from Cocos nucifera water and evaluation of antibacterial activity on four bacterial strains in Center, Cameroon. Asian J Nat Prod Biochem 22: 27-34. In 2017, the WHO published its first list of “priority pathogens” resistant to antibiotics to combat growing antimicrobial resistance globally. These include bacteria that are multi-resistant to several antibiotics (Acinetobacter, Escherichia, etc.) and others (Salmonella, Shigella, etc.). Currently, research is focused on new antibiotics and medicinal plants are among the favored natural resources. Worldwide, Cocos nucifera water (Arecaceae) or coconut water, is traditionally reported to fight bacterial diseases. Unfortunately, information is lacking on its antibacterial potential in Center, Cameroon. The aim is to determine the traditional antibacterial uses of this water in Central, Cameroon. Then, transform this water into Improved Traditional Medicine (ITM). Finally, evaluate the antibacterial activity of ITM on 4 bacterial strains following the respective Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of 0.015 and 0.25 µg/mL. The methods were ethnomedicinal surveys, the pre-formulation protocol of medicinal syrup, and sensitivity tests in liquid and solid media. Therefore, 76 informants belonging to several ethnolinguistic groups participated. Women (55.27%) exceed men (44.73%) traditionally used coconut water more to treat digestive disorders (stomachache and constipation). An antibacterial ITM named Coco Water Cure (CWC) was manufactured. The more sensitive Salmonella enteritidis and Shigella dysenteriae bacteria with CWC had an MIC of 0.25 µL/mL, respectively. In conclusion, coconut water containing actives compounds such as lauric acid is eligible among the natural antibiotic resources from Center, Cameroon.

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