Compound identifications from methanol extract of kepel fruit flesh (Stelechocarpus burahol)

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DEWI SUNDARI
DESI SUCI HANDAYANI
VENTY SURYANTI

Abstract

Abstract. Sundari D, Handayani DS, Suryanti V. 2023. Identification of compounds from methanol extract of kepel fruit flesh (Stelechocarpus burahol). Pros Sem Nas Masy Biodiv Indon 9: 86-90. The abundant biodiversity in Indonesia has various types of species. One is the diversity in the Annonaceae family, the Stelechocarpus genus, with the Kepel species (Stelechocarpus burahol (BI.) Hook & Th.). The part of the Kepel tree that has been used is in the form of leaves and fruit. Kepel fruit is widely used for table dishes fruits, cosmetic ingredients, deodorants, perfumes, long-lasting herbal medicine, and as a natural antioxidant. Currently, little is known about the compound ingredients contained in Kepel fruit. This study aims to identify the compounds in the Kepel fruit flesh's methanol extract. The compound extraction method used solid-liquid maceration and identified using Liquid Chromatography-Mass Spectrometry (LC-MS). Kepel fruit phytochemicals include saponins, flavonoids, and tannins. The results showed that the methanol extract of Kepel fruit flesh contained the compound (3S)-N-[(2S)-3-(1H-indole-3-yl)-1-(3-methoxyanilino)-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamid, norwogonin, chikutsu saponin IV and epicatechin. The identified compounds from the extract can be used as anti-inflammatory, antimutagen, anti-carcinogenic, antimicrobial, and antioxidant because flavonoid compounds potentially have biological/medicinal activity.

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References
Agustina E, Andiarna F, Lusiana N, Purnamasari R, Hadi MI. 2018. Identifikasi senyawa aktif dari ekstrak daun jambu air (Syzygium aqueum) dengan perbandingan beberapa pelarut pada metode maserasi. Biotropic?: J Trop Biol 2 (2): 108-118. DOI: 10.29080/biotropic.2018.2.2.108-118. [Indonesian]
Agustina S, Ruslan, Wiraningtyas A. 2016. Skrining fitokimia tanaman obat di Kabupaten Bima. Cakra Kimia (Indonesian E-Journal of Applied Chemistry) 4 (1): 71-76. [Indonesian]
Arifin B, Ibrahim S. 2018. Struktur, bioaktivitas dan antioksidan flavonoid. Jurnal Zarah 6 (1): 21-29. DOI: 10.31629/zarah.v6i1.313. [Indonesian]
Batubara I, Darusman LK, Djauhari E, Mitsunaga T. 2010. Potency of kepel (Stelechocarpus burahol) as cyclooxigenase-2 inhibitor. Indonesian J Plant Med 3 (2): 142078.
Cannon JG, Burton RA, Wood SG, Owen NL. 2004. Naturally occurring fish poisons from plants. J Chem Educ 81 (10): 1457-1461. DOI: 10.1021/ed081p1457.
Geiger J, Armitage RA DeRoo CS. 2012. Identification of organic dyes by direct analysis in real time-time of flight mass spectrometry. ACS Symp Ser 1103: 123-129. doi: 10.1021/bk-2012-1103.ch006.
Haryjanto L. 2012. Konservasi kepel (Stelechocarpus Burahol (Blume) Hook. f. & Thomson): Jenis yang telah langka. Mitra Hutan Tanaman 7 (1): 11-17. [Indonesian]
Heriyanto NM, Garsetiasih R. 2007. Kajian ekologi pohon burahol (Stelechocarpus burahol) di Taman Nasional Meru Betiri, Jawa Timur. Buletin Plasma Nutfah 11 (2): 65-73. DOI: 10.21082/blpn.v11n2.2005.p65-73. [Indonesian]
Kacjan Marši? N, Gašperlin L, Abram V, Budi? M, Vidrih R. 2011. Quality parameters and total phenolic content in tomato fruits regarding cultivar and microclimatic conditions. Turkish J Agric For 35 (2): 185-194. DOI: 10.3906/tar-0910-499.
Marliana SD, Suryanti V, Suyono. 2005. Skrining fitokimia dan analisis kromatografi lapis tipis komponen kimia buah labu siam (Sechium edule Jacq . Swartz .) dalam ekstrak etanol. Biofarmasi 3 (1): 26-31. [Indonesian]
Ramadhan BC, Aziz SA, Ghulamahdi M. 2016. Potensi kadar bioaktif yang terdapat pada daun kepel (Stelechocarpus burahol). Buletin Penelitian Tanaman Rempah dan Obat 26 (2): 99-108. DOI: 10.21082/bullittro.v26n2.2015.99-108. [Indonesian]
Rasidah, Syahmani, Iriani R. 2019. Identifikasi senyawa flavonoid dari kulit batang tanaman rambai padi (Sonneratia alba) dan uji aktivitasnya sebagai antibakteri Staphylococcus aureus. Jurnal Jejaring Matematika dan Sains 1 (2): 97-106. DOI: 10.36873/jjms.v1i2.217. [Indonesian]
Sangi M, Runtuwene MRJ, Simbala HEI. 2008. Analisa fitokimia obat di Minahasa Utara. Chemistry Progres 1 (1): 47-53. [Indonesian]
Sofyan A, Widodo E, Natsir H. 2017. Bioactive component, antioxidant activity, and fatty acid profile of red beewort (Acorus sp.) and white beewort (Acorus calamus). Jurnal Teknologi Pertanian 18 (3): 173-180. DOI: 10.21776/ub.jtp.2017.018.03.17. [Indonesian]
Sousa HG, Uchôa VT, Cavalcanti SMG, de Almeida PM, Chaves MH, Lima Neto JDS, Nunes PHM, da Costa Júnior JS, Rai M, Do Carmo IS, de Sousa EA. 2021. Phytochemical screening, phenolic and flavonoid contents, antioxidant and cytogenotoxicity activities of Combretum leprosum Mart. (Combretaceae). J Toxicol Environ Health-Part A: Curr Issues 84 (10): 399-417. DOI: 10.1080/15287394.2021.1875345.
Sunardi C, Sumiwi SA, Hertati A. 2010. Penelitian antiimplantasi ekstrak etanol daging buah burahol (Stelechocarpus burahol Hook F. Thomson) pada tikus putih. Majalah Ilmu Kefarmasian 7 (1): 1-8. [Indonesian]
Sunarni T. 2007. Flavonoid antioksidan penangkap radikal dari daun kepel (Stelechocarpus burahol (Bl.) Hook f. & Th.). Majalah Farmasi Indonesia 18 (3): 111-116. [Indonesian]
Suparmi S, Isradji I, Yusuf I, Fatmawati D, Ratnaningrum IH, Fuadiyah S, Wahyuni II, Dini AR. 2015. Anti-implantation activity of kepel (Stelechocarpus burahol) pulp ethanol extract in female mice. J Pure Appl Chem Res 4 (3): 94-99. DOI: 10.21776/ub.jpacr.2015.004.03.220.
Wowor MGG, Tampara J, Suryanto E, Momuat LI. 2022. Skrining fitokimia dan uji antibakteri masker peel-off ekstrak etanol daun kalu burung (Barleria prionitis L.). Jurnal Ilmiah Sains 22 (1): 75-86. DOI: 10.35799/jis.v22i1.38954. [Indonesian]
Yadav M, Chatterji S, Gupta SK, Watal G. 2014. Preliminary phytochemical screening of six medicinal plants used in traditional medicine. Intl J Pharm Pharm Sci 6 (5): 539-542.